Nucleotide Market size – USD 550.10 Million in 2021, Growth – CAGR of 5.9%, Trends – Increasing use of next-generation sequencing methods for studying viral pathogens 

The global Nucleotide Market size is expected to reach USD 926.18 Million in 2030 and register a revenue CAGR of 5.9%, according to the latest report by Reports and Data. Key factors, such as rising demand for nucleotides in the Food Beverage (FB) industry and increasing demand for dietary nucleotides are driving global market revenue growth. 

In addition, increasing nucleotide application in various end-use industries such as pharmaceuticals, food beverage additives, animal feed additives, and diagnostic testing is driving revenue growth of the market. Growing customer consciousness of adverse effects of savory ingredients is estimated to spur demand for a nucleotide-based flavoring agent. Moreover, advancements in methods is another factor anticipated to foster market revenue growth during the forecast period. Nucleotides are synthesized endogenously and have important effects on growth and development of cells with a high turnover rate such as those in the immune system and digestive tract. Nucleoproteins and nucleic acids, which are present in various amounts in many foods, such as lamb, liver, and mushrooms, are dietary sources of nucleotides. Furthermore, increasing demand for nucleotide-rich food items will drive revenue growth of the market between 2022 and 2030.

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Top Leading Players in The Global Nucleotides Market Are:

Geneaid Biotech Ltd., MCLAB, ProMega Corporation, PurMaBiologics, QIAGEN, Takara Bio, Inc., Thermo Fisher Scientific, TransGen Biotech Co., Ltd., PolyOrg, Inc., Zymo Research Corporation, Trilink Biotechnologies, Inc., Meridian Bioscience, LGC Biosearch Technologies, BOC Sciences, Ajinomoto Co., Inc., Merck KGaA, PerkinElmer, Inc., and Jena Bioscience GmbH. 

Some Key Highlights from the Report:

• Based on technology, the TaqMan Allelic Discrimination segment was valued at USD 206.23 Million in 2021 and is expected to be valued at USD 325.37 Million by 2030, growing at a CAGR of 5.1% during the forecast period. Allelic discrimination assays are widely used in academic and research laboratories for genotyping frame shifts, point mutations, as well as small (six base pair length) insertions and deletions. TaqMan allelic discrimination assays use a TaqMan probe for detecting specific alleles in Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) samples. The assay enables researchers to rapidly detect allelic variations observed in samples of patients with genetic disorders. Furthermore, rising prevalence of viral diseases is expected to further increase demand of this assay, thereby driving revenue growth of this segment during the forecast period.
• Based on application, the molecular biology segment is projected to account for a significant revenue share over the forecast period. Diagnostics and treatment of human diseases have been facilitated by genomic technology developments. In genetics, introduction of molecular technology has led to development of novel approaches for diagnostic and predictive DNA analysis that are increasingly specific, quick, and trustworthy. In addition, production of nucleic acid analogues has become an important aspect of modern biology, due to potential application of these new biomarkers in genetic diagnosis and research. In the past decade, nucleic acids have been widely changed by substituting neutral or charged structures for phosphodiester linker or sugar-phosphodiester backbone. Several of these modified oligonucleotides exhibit enhanced Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) affinity and binding characteristics. Locked Nucleic Acids (LNAs), also known as Bridging Nucleic Acids (BNAs) and Peptide Nucleic Acids (PNAs) are two prominent representations of this new form of oligomers.
• Based on end-user, the academic and research institutes segment accounted for a significant revenue share in 2021. Rising number of research initiatives for whole genome-sequencing and replication of nucleic acid for disease diagnosis and identification of novel biomarkers are major factors contributing to revenue growth of the nucleotide market. Recent research studies have conducted Genome-Wide Association Studies (GWAS) of diseases, such as insomnia and hip osteoarthritis, to genotype loci that influence intensity of disease. Genetic information regarding Substance-Use Disorders (SUDs) can be also obtained using GWAS. Furthermore, increasing number of sequencing and drug development research studies is expected to drive adoption of nucleotides in academic and research institutes and drive revenue growth of this segment over the forecast period.
• The North America market is expected to register a rapid revenue CAGR in the global Nucleotide market over the forecast period owing to increased consumer interest in nutritious food products. Also, growing self-medication coupled with increasing knowledge about health safety is expected to drive revenue growth of the market. For example, on 12 February 2022, according to the data from Centers for Disease Control and Prevention, foodborne infections affect 48 million Americans (1 in 6) each year, resulting in 128,000 hospitalizations and 3,000 deaths. Moreover, rising demand for proper dietary supplements to overcome such type of disease is expected to drive demand for nucleotides and revenue growth of the market.

Segments covered in the report:

Product Outlook (Revenue, USD Million, 2019 - 2030)

• Laboratory Grade
• Deoxynucleotide Triphosphates (dNTPs)
• Deoxyadenosine Triphosphate (dATP)
• Deoxycytidine Triphosphate (dCTP)
• Deoxyguanosine Triphosphate (dGTP)
• Thymidine Triphosphate (dTTP)
• Nucleoside Triphosphates (NTPs)
• Adenosine Triphosphate (ATP)
• Tetrahydrogen Triphosphate (CTP)
• Guanosine-5’-Triphosphate (GTP)
• Uridine Triphosphate (UTP)
• Modified Nucleotides
• Fluorescently-labeled Nucleotides
• Biotin-labeled Nucleotides
• Linker-modified Nucleotides
• Cap Analog and Variants
• Industry Grade
• Food Grade

Concentration Outlook (Revenue, USD Million, 2019 - 2030)

• 2-5 mM
• 5-10 mM
• 10-25 mM
• 25-100 mM

Technology Outlook (Revenue, USD Million, 2019 - 2030)

• TaqMan Allelic Discrimination
• Gene Chips Microarrays
• SNP by Pyrosequencing
• Other Technologies

Application Outlook (Revenue, USD Million, 2019 - 2030)

• Pharmaceutical Research
• Diagnostic Application
• Molecular Biology
• PCR
• Reverse Transcriptase
• DNA Labeling
• Other Molecular Biology
• Food and Beverage Additive
• Animal Feed Additive
• Other Applications

End-User Outlook (Revenue, USD Million, 2019 - 2030)

• Pharmaceutical and Biotechnology Companies
• Diagnostic Labs
• Academic and Research Institutes
• Other End-users

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Nucleotides Market Upcoming Growth:

Nucleotides are organic molecules that serve as the building blocks of nucleic acids such as DNA and RNA. They are used in a variety of applications such as infant formula, functional food and beverages, pharmaceuticals, and animal feed.

The global nucleotides market is expected to grow due to the increasing demand for nucleotides in infant formula and functional food and beverages. Nucleotides are added to infant formula to mimic the nucleotide content of breast milk, which has been found to have beneficial effects on infant health.

In addition, nucleotides are added to functional food and beverages to enhance their nutritional value and provide health benefits such as improved immunity and gut health.

The pharmaceutical industry is also expected to contribute to the growth of the nucleotides market, as nucleotides are used in the development of drugs for various diseases such as cancer, viral infections, and genetic disorders.

The animal feed industry is another key market for nucleotides, as they are added to animal feed to improve animal health and performance.

Furthermore, the development of new technologies for the production of nucleotides is expected to create new opportunities for growth in the market.

Overall, the nucleotides market is expected to experience steady growth in the coming years due to the increasing demand for nucleotides in various applications and the development of new technologies for their production.

Regional Outlook:

• North America (U.S.A., Canada, Mexico)
• Europe (Italy, U.K., Germany, France, Rest of Europe)
• Asia Pacific (China, India, Japan, South Korea, Australia, Rest of APAC)
• Latin America (Chile, Brazil, Argentina, Peru, Rest of Latin America)
• Middle East Africa (Saudi Arabia, U.A.E., South Africa, Rest of MEA)

Key Questions Addressed in the Report:

• What are the dominating factors that are influencing the growth of the industry?
• In the forecast period, which market segment is expected to rise the most?
• What are the risks and challenges that the industry is facing?
• In the coming years, which area is projected to dominate the market?
• Who are the major players in the market?
• What kind of strategic business plans have they made?

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